Job Listing Description

Scientist II

Chipton-Ross is seeking a Scientist II for an opening in Princeton, NJ.

Acts as a key scientist in the upstream group within the BioProcess Sciences division of the Pharma Services Group. Responsible for the execution of and hands on support of projects such as the development and characterization of mammalian cell lines for the clinical/ commercial manufacture of recombinant protein products.

Provides moderately complex analyses in a biology environment within defined procedures and practices. Participates in the execution of projects developing mammalian cell culture processes, with activities including cell line generation, clone and media/feed screening using ambr technology. Participates in the development of scalable processes with improved product yield and reduced costs in a biologics environment. Makes detailed observations and reviews, documents, and communicates test results; recommends solutions. Maintains lab equipment.

Technical/scientific project activities to execute strategies and technical solutions that meet project needs and deliverables. Assists with the design of experimental plans based on the defined deliverables. Conducts semi-routine and moderately complex tasks and sample analyses to support process development. Works with process development and manufacture groups to trouble-shoot process challenges. Performs key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening, characterization of clonal cell lines using scale-down models, cell banking, and cell line stability studies. Develops mammalian cell culture processes to support the production and manufacturing of recombinant proteins (including mAbs) under varying levels of direction, including, but not limited to cell culture scaleup, media development, harvest (recovery), process range finding, and statistical analysis of data. Performs media optimization, bioreactor process development, and cell culture clarification. Records results in notebook accurately, clearly, and regularly. Assists with preparing protocols, reports, and test methods. Maintains and ensures safe laboratory environment and work practices. Helps to maintain laboratory and order common supplies. Executes, records, and evaluates experimental data appropriately, including the writing and revising of process development reports and technology transfer protocols as needed.

With Bachelor's degree, minimum of 2 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory. Relevant industry experience preferred. Demonstrated experience in routine cell and molecular biology techniques. Upstream bioprocessing experience utilizing mammalian cell cultures; experienced in designing and optimizing cell culture processes with manufacturing in mind. Experience using advanced statistical software packages and experience with design of experiments (DoE) software (i.e. MiniTab, JMP) preferred. Working knowledge of GMP/ GLP regulations relating to cell lines for biopharmaceuticals. Strong MS Excel, PowerPoint and Word skills. Microsoft Project skills preferred. Experience with high throughput automation is a plus.

Accredited Bachelorís degree or Master's degree in biology, chemistry, biochemistry, chemical engineering, or a related field.


Job Number: 187368
Job Location: Princeton, NJ
Rate: Up to $33.17 DOE
Duration: 3 mos
Input Date: 09/21/2020
Last Updated: 10/27/2020
Attention: Tyler Harrell
Address: 420 CULVER BLVD
City, State: PLAYA DEL REY, CA 90293
Phone: 310/414-7800 X286
800 Phone: 800/927-9318
Fax Phone: 310/414-7808

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